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Blob Supplementary file 5: Percentile scores

Created: 2016-10-25 15:05:47

Credits: User Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This document presents the percentile score of the prioritized gene list when compared to the frequency distribution of 100 match scores of randomly sampled gene-HTT concept pairs out of the 12,391 genes in our concept profile database.

File type: Plain text

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Blob Supplementary file 4: Decision about the promoter re...

Created: 2016-10-25 15:05:15

Credits: User Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This document is included as a reference to describe the decisions that were made concerning the promoter size using an older version of epigenetic data from ENCODE. In this file we present the additional runs of the workflow compute\_overlaps that were performed with different parameters in order to test and decide for the best promoter region and overlap parameters. 

File type: Word document

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Blob Supplementary file 3: Gene prioritization

Created: 2016-10-25 15:04:40

Credits: User Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Top 100 novel proteins, resulted from the semantic analysis associated with HTT and epigenetics

File type: Excel workbook

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Blob Supplementary file 2: Annotations of CpG containing ...

Created: 2016-10-25 15:03:45

Credits: User Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

The top 50 annotations characterising each group of genes with CpG islands and without, resulted from the semantic analysis of those two groups of genes with Biological Processes. 

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Blob Supplementary file 1: Unique annotations of genes in...

Created: 2016-10-25 15:01:52

Credits: User Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This file contains the results from the semantic analysis with Biological Processes of the genes that were overlapping with active TSS, bivalent TSS, heterochromatin and repressed polycomb chromatin state. The annotations that we present here are uniquely characterizing each gene list (as resulted from the CPA out of the top 50 annotations). 

File type: Plain text

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Blob mySketch

Created: 2016-10-25 14:00:09

Credits: User tibco tibco

License: Creative Commons Attribution-Share Alike 3.0 Unported License

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File type: PNG image

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Blob GGTase

Created: 2016-10-24 06:00:22

Credits: User Henrry Mo

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase (GGTase 1) adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins bearing a CaaX motif:a four-amino acid sequence at the carboxyl terminal of a protein. Geranylgeranyltransferase inhibitors are being investigated as anti-cancer agents.

File type: GIF image

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Blob Water in Literature Aspects (Social and Cultural Asp...

Created: 2016-10-15 17:13:06

Credits: User Dr Kaveh Ostad Ali Askari

License: Creative Commons Attribution-Share Alike 3.0 Unported License

The type of water in a story or novel is just as important as the fact that water is used as a symbol. Rivers often represent the flow of life or fertility. Rivers are typically used as symbols by authors because rivers flow; they are constantly moving and they follow a distinct path. Oceans, on the other hand, because of their scope in relation to the earth, often represent obstacles or abysses from which things emerge or that characters must journey across to reach a destination. Oceans are...

File type: JPEG image

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Blob Alexandru Mischie - Head-to-Head Comparison of Sirol...

Created: 2016-09-16 22:29:09

Credits: User ALEXANDRU MISCHIE

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Alexandru Mischie - Head-to-Head Comparison of Sirolimus-Eluting Stent Versus Bare Metal Stent Evaluation of the Coronary Endothelial Dysfunction in the Same Patient Presenting with Multiple Coronary Artery Lesions The CREDENTIAL study

File type: Adobe PDF

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Blob Alexandru Mischie - Successful management of ostial ...

Created: 2016-09-16 22:26:06

Credits: User ALEXANDRU MISCHIE

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Case report about ostial left main thrombus treated with systemic thrombolysis

File type: Adobe PDF

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