User: Irb1109
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Name: Irb1109 Joined: Thursday 29 November 2007 16:58:37 (UTC) Email (public): i.r.booth [at] abdn.ac.uk Website: http://www.abdn.ac.uk/ims/staff/details.php?id=i.r.booth Location: Aberdeen, United Kingdom |
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One of our major research activities is the analysis of the structure and function of bacterial ion channels and efflux systems. E. coli cells possess at least four classes of ion channels - mechanosensitive (MscL, MscS, MscM, KefA), ligand-gated (KefB, KefC), Shaker-like (Kch) and chloride (CLC). Our work on MscS, MscK and KefC has advanced to the stage where the physiological role of the channels is understood, the principal basis of gating is clear and molecular analysis of the gating is quite advanced. Our major goals are to marry the genetic and physiological insights with structural information through protein biochemistry and crystallography.
Other contact details:
Not specifiedInterests:
homeostasis in bacteria; bacterial ion channels and regulated trasnporters involved in homeostasis; stress adaptation.
Field/Industry: Microbiology
Occupation/Role(s): Professor
Organisation(s):
Univefrsity of Aberdeen
