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Supplementary file 5: Percentile scores

Created: 2016-10-25 15:05:47

Credits: Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This document presents the percentile score of the prioritized gene list when compared to the frequency distribution of 100 match scores of randomly sampled gene-HTT concept pairs out of the 12,391 genes in our concept profile database.

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Supplementary file 4: Decision about the promoter re...

Created: 2016-10-25 15:05:15

Credits: Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This document is included as a reference to describe the decisions that were made concerning the promoter size using an older version of epigenetic data from ENCODE. In this file we present the additional runs of the workflow compute\_overlaps that were performed with different parameters in order to test and decide for the best promoter region and overlap parameters.

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Supplementary file 3: Gene prioritization

Created: 2016-10-25 15:04:40

Credits: Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Top 100 novel proteins, resulted from the semantic analysis associated with HTT and epigenetics

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Supplementary file 2: Annotations of CpG containing ...

Created: 2016-10-25 15:03:45

Credits: Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

The top 50 annotations characterising each group of genes with CpG islands and without, resulted from the semantic analysis of those two groups of genes with Biological Processes.

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Supplementary file 1: Unique annotations of genes in...

Created: 2016-10-25 15:01:52

Credits: Eleni

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This file contains the results from the semantic analysis with Biological Processes of the genes that were overlapping with active TSS, bivalent TSS, heterochromatin and repressed polycomb chromatin state. The annotations that we present here are uniquely characterizing each gene list (as resulted from the CPA out of the top 50 annotations).

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converter_nanopublications

Created: 2015-04-03 21:08:40

Credits: Eleni BioSemantics