Content from the BioSemantics drug discovery group

Get targets for compound (1)

• Download

This workflow retrieves single protein targets for a compound from open PHACTS.

Created: 2016-02-22

Credits: Kristina Hettne Eelke van der Horst Aylin Metzner

Get similar phenotypes for a disease and a... (1)

• Download

This workflow retrieves the similar phenotypes between a disease and a gene based on the Monarch services at http://monarchinitiative.org/page/services. Phenotype similarity is calculated based on OwlSim, see http://owlsim.org.

Created: 2016-02-22

Credits: Kristina Hettne

Get properties of drugs for genes by Entre... (3)

Given a Entrez gene_id the workflow extracts features of its protein (e.g. function, cellular localization and name) and properties of specific drugs for this protein (including activity, PSA, RO5, Smiles and molweight). This workflow uses 3 different services of OpenPHACTS (Target Pharmacology, Compound Information, Target Information).

Created: 2015-07-24 | Last updated: 2015-07-28

Credits: Katerina Nosikova Marco Roos Eleni Eelke van der Horst Elizaveta Besedina