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Epitope-based Vaccine Design Workflow using ImmunoNodes

Created: 2016-11-30 15:28:48      Last updated: 2017-04-11 18:50:27

Population-based vaccine design workflow in KNIME. AlleleFrequency is used to specify the geographical region or population of interest and returns a tab-separated list of HLA alleles with their corresponding occurrence probability within the selected population. This file, together with a FASTA file containing protein sequences, or a file containing peptides is used as input to EpitopePrediction, which generates a file containing the predicted binding affinities of the (generated) peptides and the selected HLA alleles. This file, in turn, is used as input to EpitopeSelection, which selects a user-defined number of epitopes out of the candidate pool and writes these together with other statistics into an output file.

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KNIME

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Avatar Benjamin Schubert

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Version History

In chronological order:

  1. Epitope-based Vaccine Design Workflow using ImmunoNodes

    Created by Benjamin Schubert on Wednesday 30 November 2016 15:28:48 (UTC)

  2. Epitope-based Vaccine Design Workflow using ImmunoNodes

    Created by Benjamin Schubert on Tuesday 28 March 2017 18:48:12 (UTC)

    Last edited by Benjamin Schubert on Thursday 30 March 2017 14:43:50 (UTC)

  3. Epitope-based Vaccine Design Workflow using ImmunoNodes

    Created by Benjamin Schubert on Tuesday 11 April 2017 18:49:41 (UTC)

    Last edited by Benjamin Schubert on Tuesday 11 April 2017 18:50:27 (UTC)



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