phage display techniques

Scientists have developed and commercialized a full range of innovative integrated services that are based on phage display technology. We have extensive experience in library construction and screening, antibody humanization, antibody affinity maturation, production of specific monoclonal antibodies and much more services using phage display techniques. 

Phage display is a kind of long-lasting laboratory platform for the large-scale study of molecules interaction, such as protein-protein, protein-peptide and protein-DNA interactions, and select molecules with the highest affinity for specific targets. The technology was firstly described by Smith (1985), and then be further expanded by such groups of pioneers, e.g. Greg Winter and John McCafferty (Laboratory of Molecular Biology), Richard Lerner and Carlos Barbas (Scripps Research Institute), and Frank Breitling and Stefan Dübel (German Cancer Research Center).