Q18:For pathway X, find compounds that agonize targets assayed in only functional assays with potency <1 µM.
In the Open PHACTS project, we have developed KNIME utility nodes that can be set to automatically leverage the desired content from Open PHACTS web services and simplify the construction of workflow processes. In this workflow we use the these KNIME nodes (which can be down loaded here: https://github.com/openphacts/OPS-Knime ) with the Open PHACTS API call Pathway Information: Get Targets followed byTarget Pharmacology with filters activity_type=Potency, max-activity_value=1000, activity_unit=nanomolar to answer scientific competency question Q18: For pathway X, find compounds that agonize targets assayed in only functional assays with potency <1 µM
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