Cloud Parallel Processing of Tandem Mass Spectrometry Based Proteomics Data: SpectraST Advanced

An advanced scientific workflow for searching LC−MS data using SpectraST on the cloud. Uploading the libraries is optimized to achieve better performance, which makes this workflow more suitable for processing mzXML spectra files from human samples, as the corresponding NIST library needed by SpectraST is larger than 2 GB. Here we connect 3 nested workflows, in which the first 2, i.e., decomposeMzxml and uploadToCloud, run in parallel, while the third nested workflow, i.e. runSpectrastOnCloud will start only if uploadToCloud finished all iteration. runSpectrastOnCloud and decomposeMzxml can still run in parallel.

More details can be found here: http://pubs.acs.org/doi/abs/10.1021/pr300561q