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4450?size=60x60 In Drkrish...
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Blob International Journal of Research Studies in Medical...

Created: 2020-08-21 11:22:57

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Abstract – Hydroquinone as a volatile aromatic hydrocarbon; There is a huge confusion in the public, as well as among politicians and even some scientists, about those two molecules. That confusion ultimately led to people accidently overdosing. Both molecules can be classified as 4-aminoquinolines, and both have anti-plasmodial activities, but they remain two different molecules with some different metabolites. Chloroquine has been widely used since the 1950s for prophylactic and ...

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4450?size=60x60 In Drkrish...
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Blob Antiviral nucleosides- Flu Viruses- QUINOLINES-COV...

Created: 2020-08-21 10:58:20 | Last updated: 2020-08-21 10:58:52

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Antiviral nucleosides-  Flu Viruses-                QUINOLINES-COVID-19 Hydroquinone as a volatile aromatic hydrocarbon; There is a huge confusion in the public, as well as among politicians and even some scientists, about those two molecules. That confusion ultimately led to people accidently overdosing. Both molecules can be classified as 4-aminoquinolines, and both have anti-plasmodial activities, but they...

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Blob Impact of the water quality of El-Rahawy Drain on so...

Created: 2020-07-22 10:32:45

Credits: User anas

License: Creative Commons Attribution-Share Alike 3.0 Unported License

The present study aims to evaluate the water quality of two locations in Rosetta Branch of River Nile and its histopathological and genetic adverse effects on Nile tilapia (Oreochromis niloticus). Water and fish samples were collected from up and downstream of El-Rahawy Drain discharge point (location I and II, respectively) during the summer and winter seasons. The water quality, liver histopathology and DNA alteration of fish was examined. ISSR-PCR technique wa...

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4528?size=60x60 In Insilic...
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Blob Complexity Isosteres

Created: 2020-04-27 13:28:21

Credits: User Insilicoconsulting

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Isosteric transforms generated using compounds referenced in Pubmed and whose CDK complexity descriptor is same. 

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Blob Knime Data Table for Antiviral activity multiclass P...

Created: 2020-03-25 06:18:32

Credits: User Insilicoconsulting

License: Creative Commons Attribution-Share Alike 3.0 Unported License

This is the CTD data table associated with my recent workflow Antiviral activity multiclass Predictor.

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Blob workflow as file

Created: 2020-03-18 09:00:34

Credits: User Miriam Payá

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Galaxy wf for rnaseq analysis with diff expr 

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4450?size=60x60 In Drkrish...
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Blob HCV NS3/4A 3 Protease Inhibitors: Simeprevir, Proces...

Created: 2020-02-19 06:12:03

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

In polymerase and protease drug targets and drug development, which has resulted in a strong infectious disease R&D portfolio,”and has given the company its key pipeline asset, simeprevir (TMC435), a novel protease inhibitor in Phase III clinicaldevelopment for hepatitis C that is being developed in collaboration with Janssen Pharmaceuticals. Currently, hepatitis C virus(HCV) infection is considered a serious health-care problem all over the world. A good number of direct-acting ant...

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Blob Chronic Hepatitis (Chc), Viral Polymerase Nucleotide...

Created: 2019-10-12 11:22:31

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Sofosbuvir is a viral polymerase nucleotide inhibitor that was approved in December2013 by the United States Food and Drug Administration (FDA), and in January 2014by the European Medicines Agency for the treatment of HCV infection [1]. The WHOGuidelines for the screening, care and treatment of persons with hepatitis C infectionrecommend sofosbuvir in combination with ribavirin in genotypes 1, 2, 3 and 4 HCVinfection, either with or without pegylated interferon (depending on the HCV genotype)...

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4540?size=60x60 Us Joshua Borycz
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Blob Test

Created: 2019-10-03 17:25:58

Credits: User Joshua Borycz

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Test

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Blob Bempedoic Acid a Small Molecule Drug Process and Syn...

Created: 2019-07-23 07:04:13

Credits: User Drkrishnasarmapathy

License: Creative Commons Attribution-Share Alike 3.0 Unported License

Low Density Lipoprotein Cholesterol AbstractBempedoic acid (ETC-1002), a small molecule drug, promotes low density lipoprotein (LDL) receptor mediated clearanceof LDL-cholesterol (LDL-C) by inhibition of adenosine triphosphate citrate lyase (ACL), a mechanism complementary to thoseof existing lipid-modifying therapies. Bempedoic acid is a pro-drug activated specifically within the liver where it inhibits ACL,a regulatory checkpoint within the cholesterol biosynthesis pathway. By inhibiti...

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