File Entry: Abstract Human H1N1 pandemic developed from the originally localized Mexican source early in the spring 2009. For the emergency created by the epidemic of influence of the pigs in Mexico it was correct not to create alarmism being victims of bad informati
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Title | Abstract Human H1N1 pandemic developed from the originally localized Mexican source early in the spring 2009. For the emergency created by the epidemic of influence of the pigs in Mexico it was correct not to create alarmism being victims of bad informati |
File name | OAJT.MS.ID.555593 krishnasarmapathy.pdf |
File size | 357953 |
SHA1 | 2a691cac95dc60e7ef5168c6d2b8e3c2f379e951 |
Content type | Adobe PDF |
Description
For the emergency created by the epidemic of influence of the pigs in Mexico it was correct not to create alarmisms being victims of a bad information. The possibility that the virus arrives in other parts of the world is real as for all the types of influence virus. In order that a strain has a wide distribution, its antigenic characteristics must ensure that it escapes the neutralization of antibodies of the host and of the surrounding population. The discovery of a new, biologic Host-Defense protein, “HDFx”, may provide a unique way to ameliorate and prevent the “cytokine storms” and haemorrhages seen in severe influenza infections. The influenza A virus subtypes H1N1, H1N2 and H3N2 are prevalent in pig populations worldwide. All scientific data point towards swine as the key host species for new human influenza pandemics, which have been suggested to evolve in pigs from viral genes of avian, human and porcine origin. Therefore, it is of major importance torecord the evolution of swine influenza viruses in pigs, and in particular monitor hallmarks of adaptation to humans. The scope of this paper was to increase the understanding of the genetics of Swine Influenza Virus (SIV), and to investigate the importance of different viral gene markers in association with differences in pathogenicity of two viruses of H1N2 subtype in pigs. The results from this study demonstrate, for the first time, natural reassortment in H1N2 viruses in the pig populations of Sweden as well as in india.
So the outbreaks will happen with those strains that have dominant antigens that fit the deficiency, or better, the abscences of antibody in the population. It seems, in conclusion that the flu virus showes an ability and an aptitude for survival built on the possibility of émergence of new models that allow the virus being confused easily through populations still partly immune to previous antigenic forms. According to this view, the changes in the influenza A can be designed in single meaning, in the context of a principle and of an evelutionary progress, from Burnet said immunological drift or steering immunology. The antiviral drugs (inhibitors of the neuraminidasis, receptor of the virus surface) should be assumed within 48 hours by the appearance of the influence symptoms and for the subjects that have had a close contact with people infected by the flu virus. The vaccination against the influence is the most effective method to prevent the illness. From the moment that we find the isolation of a new flu virus, we must wait for the preparation of a new specific vaccine that will be ready for the next influence season in Autumn.
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