File Entry: GGTase
Created: 2016-10-24 06:00:22
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Title | GGTase |
File name | creative enzymes.gif |
File size | 12748 |
SHA1 | a5274acc9d3aa157c5c288ee4cae5bb2a4923dd6 |
Content type | GIF image |
Description
Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase (GGTase 1) adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins bearing a CaaX motif:a four-amino acid sequence at the carboxyl terminal of a protein. Geranylgeranyltransferase inhibitors are being investigated as anti-cancer agents.
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