Title: Towards Genotype-Phenotype Correlations
It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically processing large datasets, and represent a framework for the re-use and the explicit declaration of experimental methods. In this pack is a paper which describes the issues facing the manual analysis of microarray and QTL data for the discovery of candidate genes underlying complex phenotypes. Our methodology was applied to a use case of resistance to African trypanosomiasis in the mouse. Workflows developed in this investigation, including a guide to loading and executing them with example data, are available within this pack.
Supplimentary information is provided in this pack.
File: A Systematic Strategy for Large-Scale Analysis of Genotype-Phenotype Correlations: Identification of candidate genes involved in African Trypanosomiasis (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:23:31) |
File: Authors table (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:36:23) |
File: Candidate Gene protocol (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:27:53) |
File: Ensembl database release (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 18:04:50) |
File: Ensembl gene report (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:30:29) |
File: Kegg gene descriptions (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 18:06:41) |
File: Kegg pathway descriptions (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:28:17) |
File: Kegg pathway identifiers (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:29:04) |
File: Kegg Pathway release (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:25:32) |
File: Kegg pathways and genes (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:26:46) |
Workflow: KEGG pathways common to both QTL and microarray based investigations (Paul Fisher)
Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:18:55) |
File: Kegg-Uniprot-Entrez cross-references (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 19:24:07) |
Workflow: Mouse Microarray Analysis (Paul Fisher)
Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:18:26) |
Pack: Pathway to Phenotype using Text Mining (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-08-11 14:50:01) |
Workflow: Pathways and Gene annotations for QTL region (Paul Fisher)
Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:17:26) |
File: Re-sequenced Daxx gene info (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:54:10) |
File: Table of SNP sequenceing results (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 13:29:50) |
File: Tir1 QTL - Day 3 Microarray intersecting pathways (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:56:29) |
File: Tir1 QTL - microarray day 7 intersecting pathways (Paul Fisher) Added by Paul Fisher ... more than 1 year ago (2009-04-08 17:58:14) |
External: Link - (http://www.slideshare.net/fisherp/a-systematic-approach-to-genotypephenotype-correlations) Added by Paul Fisher ... more than 1 year ago (2009-08-10 12:38:06) |
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